Effect of pistachio consumption on the modulation of urinary gut microbiota-related metabolites in prediabetic subjects.

Hernández-Alonso P, Cañueto D, Giardina S, et al.

J Nutr Biochem. 2017;45:48-53.

Changes in the composition of intestinal microorganisms (microbiota) may impact metabolic and heart disease as well as longevity. This cross-over study investigated whether daily intake of pistachios could change urinary metabolites associated with the activity of gut microbiota in prediabetic subjects.

Investigators found that indeed pistachio consumption can modify the urinary profile of these metabolites. The changes were in the expected direction according to a beneficial effect of pistachio consumption on insulin resistance and Type 2 diabetes.

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