Photoprotection by pistachio bioactives in a 3-dimensional human skin equivalent tissue model.

Chen CO, Smith A, Liu Y, Du P, Blumberg JB, Garlick J.

International Journal of Food Sciences and Nutrition. vol. 68,6 (2017): 712-718.

Investigators used a 3-dimensional human skin equivalent (HSE) tissue model which closely mimics human skin and examined whether pistachios antioxidants, lutein and c-tocopherol, the predominant lipophilic antioxidants, would prevent damage to the HSE when exposed to UVA radiation.

The pistachio antioxidants preserved overall skin thickness and organization, as well as fibroblast morphology, in HSE exposed to the UVA irradiation. The positive impact of lutein and c-tocopherol on UVA-induced morphological changes and the preservation of HSE by pistachio extracts implicate a potential role of pistachio consumption in promoting skin health. Additional studies are warranted to investigate the potential role of pistachio bioactives promoting skin health.

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Photoprotection by pistachio bioactives in a 3-dimensional human skin equivalent tissue model.

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