The Antioxidant Activity of Pistachios Reduces Cardiac Tissue Injury of Acute Ischemia/Reperfusion (I/R) In Diabetic Streptozotocin (STZ)-Induced Hyperglycaemic Rats.

Di Paola R, Fusco R, Gugliandolo E, et al.

Front Pharmacol. 2018;9:51.

This study evaluated the antioxidant properties of raw or roasted salted pistachios on reperfusion injury in diabetic rats. Reperfusion injury refers to oxidative damage to the heart that happens when blood flow is restored to the tissue after a heart attack. Because pistachios are an excellent source of antioxidants, investigators predicted that they could have a protective effect in this process.

The investigators measured markers of inflammation, oxidative damage and tissue injury in animals pre-treated with pistachios. Investigators showed that pistachios reduced tissue damage of reperfusion and lowered markers of inflammation. While the effects of raw pistachios were higher than those of roasted pistachios, results indicate that pistachios can modulate the inflammatory process associated with reperfusion

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The Antioxidant Activity of Pistachios Reduces Cardiac Tissue Injury of Acute Ischemia/Reperfusion (I/R) In Diabetic Streptozotocin (STZ)-Induced Hyperglycaemic Rats.

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